Micrococcin cysteine-to-thiazole conversion through transient interactions between a scaffolding protein and two modification enzymes

Ribosomally synthesized and post-translationally modified peptides (RiPPs) are a broad group of compounds mediating microbial competition in nature. Azole/azoline heterocycle formation in the peptide backbone is a key step in the biosynthesis of many RiPPs. Heterocycle formation in RiPP precursors i...

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Detalles Bibliográficos
Autores principales: Calvopina-Chavez, Diana G, Bursey, Devan M, Tseng, Yi-Jie, Patil, Leena M, Bewley, Kathryn D, Bennallack, Philip R, McPhie, Josh M, Wagstaff, Kimberly B, Daley, Anisha, Miller, Susan M, Moody, James D, Price, John C, Griffitts, Joel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634744/
https://www.ncbi.nlm.nih.gov/pubmed/37961320
http://dx.doi.org/10.1101/2023.10.23.563616

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634744/
https://www.ncbi.nlm.nih.gov/pubmed/37961320
http://dx.doi.org/10.1101/2023.10.23.563616

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