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KIF1C, an RNA transporting kinesin-3, undergoes liquid-liquid phase separation through its C-terminal disordered domain

The spatial distribution of mRNA is critical for local control of protein production. Recent studies have identified the kinesin-3 family member KIF1C as an RNA transporter. However, it is not clear how KIF1C interacts with RNA molecules. Here, we show that KIF1C’s C-terminal tail domain is an intri...

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Detalles Bibliográficos
Autores principales: Geng, Qi, Keya, Jakia Jannat, Hotta, Takashi, Verhey, Kristen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634753/
https://www.ncbi.nlm.nih.gov/pubmed/37961614
http://dx.doi.org/10.1101/2023.10.23.563538