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Protein Language Models Uncover Carbohydrate-Active Enzyme Function in Metagenomics

In metagenomics, the pool of uncharacterized microbial enzymes presents a challenge for functional annotation. Among these, carbohydrate-active enzymes (CAZymes) stand out due to their pivotal roles in various biological processes related to host health and nutrition. Here, we present CAZyLingua, th...

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Detalles Bibliográficos
Autores principales: Thurimella, Kumar, Mohamed, Ahmed M. T., Graham, Daniel B., Owens, Róisín M., La Rosa, Sabina Leanti, Plichta, Damian R., Bacallado, Sergio, Xavier, Ramnik J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634757/
https://www.ncbi.nlm.nih.gov/pubmed/37961379
http://dx.doi.org/10.1101/2023.10.23.563620