Combinatorial CRISPR screens and lectin microarrays identify novel glycosylation regulators

Glycans play critical roles in cellular signaling and function. Unlike proteins, glycan structures are not templated from genes but the concerted activity of many genes, making them historically challenging to study. Here, we present a strategy that pairs pooled CRISPR screens with lectin microarray...

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Detalles Bibliográficos
Autores principales: Tsui, C Kimberly, Twells, Nicholas, Doan, Emma, Brooks, Janiya, Kulepa, Ayodeji, Webster, Brant, Mahal, Lara K, Dillin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634773/
https://www.ncbi.nlm.nih.gov/pubmed/37961200
http://dx.doi.org/10.1101/2023.10.23.563662

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634773/
https://www.ncbi.nlm.nih.gov/pubmed/37961200
http://dx.doi.org/10.1101/2023.10.23.563662

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