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Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas

Gliomas are incurable malignancies notable for an immunosuppressive microenvironment with abundant myeloid cells whose immunomodulatory properties remain poorly defined. Here, utilizing scRNA-seq data for 183,062 myeloid cells from 85 human tumors, we discover that nearly all glioma-associated myelo...

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Detalles Bibliográficos
Autores principales: Miller, Tyler E., El Farran, Chadi A., Couturier, Charles P., Chen, Zeyu, D’Antonio, Joshua P., Verga, Julia, Villanueva, Martin A., Castro, L. Nicolas Gonzalez, Tong, Yuzhou Evelyn, Saadi, Tariq Al, Chiocca, Andrew N., Fischer, David S., Heiland, Dieter Henrik, Guerriero, Jennifer L., Petrecca, Kevin, Suva, Mario L., Shalek, Alex K., Bernstein, Bradley E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634776/
https://www.ncbi.nlm.nih.gov/pubmed/37961527
http://dx.doi.org/10.1101/2023.10.24.563466