Collapse of late endosomal pH elicits a rapid Rab7 response via V-ATPase and RILP

Endosomal-lysosomal trafficking entails progressive acidification of endosomal compartments by the H(+)-V-ATPase to reach low lysosomal pH. Disruption of proper pH affects lysosomal function and the balance of protein synthesis and degradation (proteostasis). Disruption of endosomal pH also impairs...

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Detalles Bibliográficos
Autores principales: Mulligan, R.J., Magaj, M.M., Redemann, S., Yap, C.C., Winckler, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634777/
https://www.ncbi.nlm.nih.gov/pubmed/37961579
http://dx.doi.org/10.1101/2023.10.24.563658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634777/
https://www.ncbi.nlm.nih.gov/pubmed/37961579
http://dx.doi.org/10.1101/2023.10.24.563658

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