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A novel Bayesian model for assessing intratumor heterogeneity of tumor infiltrating leukocytes with multi-region gene expression sequencing

Intratumor heterogeneity (ITH) of tumor-infiltrated leukocytes (TILs) is an important phenomenon of cancer biology with potentially profound clinical impacts. Multi-region gene expression sequencing data provide a promising opportunity that allows for explorations of TILs and their intratumor hetero...

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Detalles Bibliográficos
Autores principales: Yang, Peng, Hubert, Shawna M., Futreal, P. Andrew, Song, Xingzhi, Zhang, Jianhua, Lee, J. Jack, Wistuba, Ignacio, Yuan, Ying, Zhang, Jianjun, Li, Ziyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634795/
https://www.ncbi.nlm.nih.gov/pubmed/37961165
http://dx.doi.org/10.1101/2023.10.24.563820