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Spatially resolved DNP-assisted NMR illuminates the conformational ensemble of α-synuclein in intact viable cells
The protein α-syn adopts a wide variety of conformations including an intrinsically disordered monomeric form and an α-helical rich membrane-associated form that is thought to play an important role in cellular membrane processes. However, despite the high affinity of α-syn for membranes, evidence t...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634803/ https://www.ncbi.nlm.nih.gov/pubmed/37961511 http://dx.doi.org/10.1101/2023.10.24.563877 |