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Energy metabolism modulates the regulatory impact of activators on gene expression
Gene expression is a regulated process fueled by ATP consumption. Therefore, regulation must be coupled to constraints imposed by the level of energy metabolism. Here, we explore this relationship both theoretically and experimentally. A stylized mathematical model predicts that activators of gene e...
Autores principales: | Qiao, Sha, Bernasek, Sebastian, Gallagher, Kevin D., Yamada, Shigehiro, Bagheri, Neda, Amaral, Luis A.N., Carthew, Richard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634812/ https://www.ncbi.nlm.nih.gov/pubmed/37961620 http://dx.doi.org/10.1101/2023.10.24.563842 |
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