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Highly-parallel production of designer organoids by mosaic patterning of progenitors

Human organoids are a promising approach for disease modeling and regenerative medicine. However, organoid variability and limited control over morphological outcomes remain significant challenges. Here we extend a DNA ‘velcro’ cell patterning approach, precisely controlling the number and ratio of...

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Detalles Bibliográficos
Autores principales: Porter, Catherine M., Qian, Grace C., Grindel, Samuel H., Hughes, Alex J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634829/
https://www.ncbi.nlm.nih.gov/pubmed/37961546
http://dx.doi.org/10.1101/2023.10.25.564017