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GCN5L1-mediated acetylation prevents Rictor degradation in cardiac cells after hypoxic stress
Cardiomyocyte apoptosis and cardiac fibrosis are the leading causes of mortality in patients with ischemic heart disease. As such, these processes represent potential therapeutic targets to treat heart failure resulting from ischemic insult. We previously demonstrated that the mitochondrial acetyltr...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634848/ https://www.ncbi.nlm.nih.gov/pubmed/37961692 http://dx.doi.org/10.1101/2023.10.26.564170 |