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GCN5L1-mediated acetylation prevents Rictor degradation in cardiac cells after hypoxic stress

Cardiomyocyte apoptosis and cardiac fibrosis are the leading causes of mortality in patients with ischemic heart disease. As such, these processes represent potential therapeutic targets to treat heart failure resulting from ischemic insult. We previously demonstrated that the mitochondrial acetyltr...

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Detalles Bibliográficos
Autores principales: Bugga, Paramesha, Manning, Janet R., Mushala, Bellina A.S., Stoner, Michael W., Sembrat, John, Scott, Iain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634848/
https://www.ncbi.nlm.nih.gov/pubmed/37961692
http://dx.doi.org/10.1101/2023.10.26.564170