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Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in Staphylococcus aureus

Infections caused by Staphylococcus aureus are a leading cause of mortality worldwide. S. aureus infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA) are particularly difficult to treat due to their resistance to Next Generation β-lactams (NGB) such as Methicillin, Nafcillin, Oxac...

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Detalles Bibliográficos
Autores principales: Lai, Li-Yin, Satishkumar, Nidhi, Cardozo, Sasha, Hemmadi, Vijay, Marques, Leonor B., Huang, Liusheng, Filipe, Sergio R., Pinho, Mariana G., Chambers, Henry F., Chatterjee, Som S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634853/
https://www.ncbi.nlm.nih.gov/pubmed/37961375
http://dx.doi.org/10.1101/2023.10.26.564222