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Senescence of endplate osteoclasts induces sensory innervation and spinal pain

Spinal pain affects individuals of all ages and is the most common musculoskeletal problem globally. Its clinical management remains a challenge as the underlying mechanisms leading to it are still unclear. Here, we report that greater numbers of senescent osteoclasts (SnOCs) are observed in mouse m...

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Detalles Bibliográficos
Autores principales: Pan, Dayu, Benkato, Kheiria Gamal, Han, Xuequan, Zheng, Jinjian, Kumar, Vijay, Wan, Mei, Zheng, Junying, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634856/
https://www.ncbi.nlm.nih.gov/pubmed/37961590
http://dx.doi.org/10.1101/2023.10.26.564218