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Sequence-based machine learning reveals 3D genome differences between bonobos and chimpanzees

Phenotypic divergence between closely related species, including bonobos and chimpanzees (genus Pan), is largely driven by variation in gene regulation. The 3D structure of the genome mediates gene expression; however, genome folding differences in Pan are not well understood. Here, we apply machine...

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Detalles Bibliográficos
Autores principales: Brand, Colin M., Kuang, Shuzhen, Gilbertson, Erin N., McArthur, Evonne, Pollard, Katherine S., Webster, Timothy H., Capra, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634871/
https://www.ncbi.nlm.nih.gov/pubmed/37961120
http://dx.doi.org/10.1101/2023.10.26.564272