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Sequence-based machine learning reveals 3D genome differences between bonobos and chimpanzees
Phenotypic divergence between closely related species, including bonobos and chimpanzees (genus Pan), is largely driven by variation in gene regulation. The 3D structure of the genome mediates gene expression; however, genome folding differences in Pan are not well understood. Here, we apply machine...
Autores principales: | Brand, Colin M., Kuang, Shuzhen, Gilbertson, Erin N., McArthur, Evonne, Pollard, Katherine S., Webster, Timothy H., Capra, John A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634871/ https://www.ncbi.nlm.nih.gov/pubmed/37961120 http://dx.doi.org/10.1101/2023.10.26.564272 |
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