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Determining the defining lengths between mature microRNAs/small interfering RNAs and tinyRNAs

MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are loaded into Argonaute (AGO) proteins, forming RNA-induced silencing complexes (RISCs). The assembly process establishes the seed, central, 3′ supplementary, and tail regions across the loaded guide, enabling the RISC to recognize and cleave...

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Detalles Bibliográficos
Autores principales: Sim, GeunYoung, Kehling, Audrey C., Park, Mi Seul, Divoky, Cameron, Zhang, Huaqun, Malhotra, Nipun, Secor, Jackson, Nakanishi, Kotaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634876/
https://www.ncbi.nlm.nih.gov/pubmed/37961191
http://dx.doi.org/10.1101/2023.10.27.564437