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HDAC activity is dispensable for repression of cell-cycle genes by DREAM and E2F:RB complexes

Histone deacetylases (HDACs) are pivotal in transcriptional regulation, and their dysregulation has been associated with various diseases including cancer. One of the critical roles of HDAC-containing complexes is the deacetylation of histone tails, which is canonically linked to transcriptional rep...

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Detalles Bibliográficos
Autores principales: Barrett, Alison, Shingare, Manisha R., Rechtsteiner, Andreas, Wijeratne, Tilini U., Rodriguez, Kelsie M., Rubin, Seth M., Müller, Gerd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634886/
https://www.ncbi.nlm.nih.gov/pubmed/37961464
http://dx.doi.org/10.1101/2023.10.28.564489