Cargando…

Adjusted vascular contractility relies on integrity of progranulin pathway: Insights into mitochondrial function

OBJECTIVE: Cardiovascular disease (CVD) is a global health crisis and a leading cause of mortality. The intricate interplay between vascular contractility and mitochondrial function is central to CVD pathogenesis. The progranulin gene (GRN) encodes glycoprotein progranulin (PGRN), a ubiquitous molec...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Shubhnita, Bruder-Nascimento, Ariane, Costa, Rafael M., Alves, Juliano V., Bharathi, Sivakama, Goetzman, Eric S., Bruder-Nascimento, Thiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634918/
https://www.ncbi.nlm.nih.gov/pubmed/37961631
http://dx.doi.org/10.1101/2023.10.27.564485