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Arrestin-3-assisted activation of JNK3 mediates dopaminergic behavioral and signaling plasticity in vivo

In rodents with unilateral ablation of the substantia nigra neurons supplying dopamine to the striatum, chronic treatment with the dopamine precursor L-DOPA or dopamine agonists induces a progressive increase of behavioral responses, a process known as behavioral sensitization. The sensitization is...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohamed R., Zheng, Chen, Dunning, Jeffery L., Ahmed, Mohamed S., Ge, Connie, Sanders Pair, F., Gurevich, Vsevolod V., Gurevich, Eugenia V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634923/
https://www.ncbi.nlm.nih.gov/pubmed/37961199
http://dx.doi.org/10.1101/2023.10.27.564447