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A Bayesian Framework for Cryo-EM Heterogeneity Analysis using Regularized Covariance Estimation
Proteins and the complexes they form are central to nearly all cellular processes. Their flexibility, expressed through a continuum of states, provides a window into their biological functions. Cryogenic-electron microscopy (cryo-EM) is an ideal tool to study these dynamic states as it captures spec...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634927/ https://www.ncbi.nlm.nih.gov/pubmed/37961393 http://dx.doi.org/10.1101/2023.10.28.564422 |