Inferring therapeutic vulnerability within tumors through integration of pan-cancer cell line and single-cell transcriptomic profiles

Single-cell RNA sequencing greatly advanced our understanding of intratumoral heterogeneity through identifying tumor subpopulations with distinct biologies. However, translating biological differences into treatment strategies is challenging, as we still lack tools to facilitate efficient drug disc...

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Detalles Bibliográficos
Autores principales: Zhang, Weijie, Maeser, Danielle, Lee, Adam, Huang, Yingbo, Gruener, Robert F., Abdelbar, Israa G., Jena, Sampreeti, Patel, Anand G., Huang, R. Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634928/
https://www.ncbi.nlm.nih.gov/pubmed/37961545
http://dx.doi.org/10.1101/2023.10.29.564598

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634928/
https://www.ncbi.nlm.nih.gov/pubmed/37961545
http://dx.doi.org/10.1101/2023.10.29.564598

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