Leveraging genetic correlations and multiple populations to improve genetic risk prediction for non-European populations

The disparity in genetic risk prediction accuracy between European and non-European individuals highlights a critical challenge in health inequality. To bridge this gap, we introduce JointPRS, a novel method that models multiple populations jointly to improve genetic risk predictions for non-Europea...

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Detalles Bibliográficos
Autores principales: Xu, Leqi, Zhou, Geyu, Jiang, Wei, Guan, Leying, Zhao, Hongyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634936/
https://www.ncbi.nlm.nih.gov/pubmed/37961111
http://dx.doi.org/10.1101/2023.10.29.564615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634936/
https://www.ncbi.nlm.nih.gov/pubmed/37961111
http://dx.doi.org/10.1101/2023.10.29.564615

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