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Leveraging genetic correlations and multiple populations to improve genetic risk prediction for non-European populations
The disparity in genetic risk prediction accuracy between European and non-European individuals highlights a critical challenge in health inequality. To bridge this gap, we introduce JointPRS, a novel method that models multiple populations jointly to improve genetic risk predictions for non-Europea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634936/ https://www.ncbi.nlm.nih.gov/pubmed/37961111 http://dx.doi.org/10.1101/2023.10.29.564615 |