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SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle

Apicomplexan parasites balance proliferation, persistence, and spread in their metazoan hosts. AGC kinases, such as PKG, PKA, and the PDK1 ortholog SPARK, integrate environmental signals to toggle parasites between replicative and motile life stages. Recent studies have cataloged pathways downstream...

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Detalles Bibliográficos
Autores principales: Herneisen, Alice L., Peters, Michelle L., Smith, Tyler A., Lourido, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634940/
https://www.ncbi.nlm.nih.gov/pubmed/37961644
http://dx.doi.org/10.1101/2023.10.30.564746