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SPARK regulates AGC kinases central to the Toxoplasma gondii asexual cycle
Apicomplexan parasites balance proliferation, persistence, and spread in their metazoan hosts. AGC kinases, such as PKG, PKA, and the PDK1 ortholog SPARK, integrate environmental signals to toggle parasites between replicative and motile life stages. Recent studies have cataloged pathways downstream...
Autores principales: | Herneisen, Alice L., Peters, Michelle L., Smith, Tyler A., Lourido, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634940/ https://www.ncbi.nlm.nih.gov/pubmed/37961644 http://dx.doi.org/10.1101/2023.10.30.564746 |
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