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The Evolution of Heteroresistance via Small Colony Variants in Escherichia coli Following Long Term Exposure to Bacteriostatic Antibiotics

Traditionally, bacteriostatic antibiotics are agents able to arrest bacterial growth. Despite being unable to kill bacterial cells, when they are used clinically the outcome of these drugs is frequently as effective as when a bactericidal drug is used. We explore the dynamics of Escherichia coli aft...

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Detalles Bibliográficos
Autores principales: Gil-Gil, Teresa, Berryhill, Brandon A., Manuel, Joshua A., Smith, Andrew P., McCall, Ingrid C., Baquero, Fernando, Levin, Bruce R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634941/
https://www.ncbi.nlm.nih.gov/pubmed/37961139
http://dx.doi.org/10.1101/2023.10.30.564761