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Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation
The essential stress-responsive chaperone Hsp90 impacts development and adaptation from microbes to humans. Yet despite evidence of its role in evolution, pathogenesis, and oncogenic transformation, the molecular mechanisms by which Hsp90 alters the consequences of mutations remain vigorously debate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634948/ https://www.ncbi.nlm.nih.gov/pubmed/37961536 http://dx.doi.org/10.1101/2023.10.30.564848 |