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The N6-methyladenosine demethylase ALKBH5 regulates the hypoxic HBV transcriptome.

Chronic hepatitis B is a global health problem and current treatments only suppress hepatitis B virus (HBV) infection, highlighting the need for new curative treatments. Oxygen levels influence HBV replication and we previously reported that hypoxia inducible factors (HIFs) activate the basal core p...

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Detalles Bibliográficos
Autores principales: Tsukuda, Senko, Harris, James M, Magri, Andrea, Balfe, Peter, Wing, Peter AC, Siddiqui, Aleem, McKeating, Jane A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634982/
https://www.ncbi.nlm.nih.gov/pubmed/37961409
http://dx.doi.org/10.1101/2023.10.31.564956