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Cryo-EM structure of the Spo11 core complex bound to DNA

The DNA double-strand breaks that initiate meiotic recombination are formed by topoisomerase relative Spo11, supported by conserved auxiliary factors. Because high-resolution structural data are lacking, many questions remain about the architecture of Spo11 and its partners and how they engage with...

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Detalles Bibliográficos
Autores principales: Yu, You, Wang, Juncheng, Liu, Kaixian, Zheng, Zhi, Arter, Meret, Bouuaert, Corentin Claeys, Pu, Stephen, Patel, Dinshaw J., Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634984/
https://www.ncbi.nlm.nih.gov/pubmed/37961437
http://dx.doi.org/10.1101/2023.10.31.564985