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Cryo-EM structure of the Spo11 core complex bound to DNA
The DNA double-strand breaks that initiate meiotic recombination are formed by topoisomerase relative Spo11, supported by conserved auxiliary factors. Because high-resolution structural data are lacking, many questions remain about the architecture of Spo11 and its partners and how they engage with...
Autores principales: | Yu, You, Wang, Juncheng, Liu, Kaixian, Zheng, Zhi, Arter, Meret, Bouuaert, Corentin Claeys, Pu, Stephen, Patel, Dinshaw J., Keeney, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634984/ https://www.ncbi.nlm.nih.gov/pubmed/37961437 http://dx.doi.org/10.1101/2023.10.31.564985 |
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