Legionella pneumophila exploits the endo-lysosomal network for phagosome biogenesis by co-opting SUMOylated Rab7

L. pneumophila strains harboring wild-type rpsL such as Lp02rpsL(WT) cannot replicate in mouse bone marrow-derived macrophages (BMDMs) due to induction of extensive lysosome damage and apoptosis. The mechanism of this unique infection-induced cell death remains unknown. Using a genome-wide CRISPR/Ca...

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Detalles Bibliográficos
Autores principales: Li, Chuang, Fu, Jiaqi, Shao, Shuai, Luo, Zhao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634985/
https://www.ncbi.nlm.nih.gov/pubmed/37961430
http://dx.doi.org/10.1101/2023.10.31.564884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10634985/
https://www.ncbi.nlm.nih.gov/pubmed/37961430
http://dx.doi.org/10.1101/2023.10.31.564884

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