Cargando…

Precision-Cut Liver Slices as an ex vivo model to evaluate antifibrotic therapies for liver fibrosis and cirrhosis

BACKGROUND: Precision-Cut Liver Slices (PCLS) are an ex vivo culture model developed to study hepatic drug metabolism. One of the main benefits of this model is that it retains the structure and cellular composition of the native liver. PCLS also represents a potential model system to study liver fi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yongtao, Leaker, Ben, Qiao, Guoliang, Sojoodi, Mozhdeh, Eissa, Ibrahim Ragab, Epstein, Eliana T., Eddy, Jonathan, Dimowo, Oizoshimoshiofu, Lauer, Georg M., Chung, Raymond T., Qadan, Motaz, Lanuti, Michael, Fuchs, Bryan C., Tanabe, Kenneth K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635008/
https://www.ncbi.nlm.nih.gov/pubmed/37961334
http://dx.doi.org/10.1101/2023.10.30.564772