Mechanical imbalance between normal and cancer cells drives epithelial defense against cancer

Cell competition enables normal wildtype cells of epithelial tissue to eliminate mutant cells expressing activated oncoproteins such as HRas(V12). However, the driving force behind this fundamental epithelial defense against cancer remains enigmatic. Here, we employ tissue stress microscopy and theo...

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Detalles Bibliográficos
Autores principales: Gupta, Praver, Kayal, Sayantani, Pothapragada, Shilpa P., Senapati, Harish K., Devendran, Padmashree, Bi, Dapeng, Das, Tamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635021/
https://www.ncbi.nlm.nih.gov/pubmed/37961252
http://dx.doi.org/10.1101/2023.09.27.559723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635021/
https://www.ncbi.nlm.nih.gov/pubmed/37961252
http://dx.doi.org/10.1101/2023.09.27.559723

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