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Mechanical imbalance between normal and cancer cells drives epithelial defense against cancer
Cell competition enables normal wildtype cells of epithelial tissue to eliminate mutant cells expressing activated oncoproteins such as HRas(V12). However, the driving force behind this fundamental epithelial defense against cancer remains enigmatic. Here, we employ tissue stress microscopy and theo...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635021/ https://www.ncbi.nlm.nih.gov/pubmed/37961252 http://dx.doi.org/10.1101/2023.09.27.559723 |