Autophagy regulates tumor growth and metastasis

The role of autophagy in tumorigenesis and tumor metastasis remains poorly understood. Here we show that inhibition of autophagy stabilizes the transcription factor Twist1 through Sequestosome-1 (SQSTM1, also known as p62) and thus increases cell proliferation, migration, and epithelial-mesenchymal...

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Detalles Bibliográficos
Autores principales: Qiang, Lei, Zhao, Baozhong, Ming, Mei, Wang, Ning, He, Tong-Chuan, Hwang, Seungmin, Thorburn, Andrew, He, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635024/
https://www.ncbi.nlm.nih.gov/pubmed/37961427
http://dx.doi.org/10.1101/2023.10.31.564991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635024/
https://www.ncbi.nlm.nih.gov/pubmed/37961427
http://dx.doi.org/10.1101/2023.10.31.564991

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