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Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR

CC-chemokine ligand 2 (CCL2) is involved in the pathogenesis of several diseases associated with monocyte/macrophage recruitment, such as HIV-associated neurocognitive disorder (HAND), tuberculosis, and atherosclerosis. The rs1024611 (alleles:A>G; G is the risk allele) polymorphism in the CCL2 ci...

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Detalles Bibliográficos
Autores principales: Akhtar, Feroz, Ruiz, Joselin Hernandez, Liu, Ya-Guang, Resendez, Roy G., Feliers, Denis, Morales, Liza D., Diaz-Badillo, Alvaro, Lehman, Donna M., Arya, Rector, Lopez-Alvarenga, Juan Carlos, Blangero, John, Duggirala, Ravindranath, Mummidi, Srinivas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635030/
https://www.ncbi.nlm.nih.gov/pubmed/37961304
http://dx.doi.org/10.1101/2023.10.31.564937