Cargando…

Functional characterization of the disease-associated CCL2 rs1024611G-rs13900T haplotype: The role of the RNA-binding protein HuR

CC-chemokine ligand 2 (CCL2) is involved in the pathogenesis of several diseases associated with monocyte/macrophage recruitment, such as HIV-associated neurocognitive disorder (HAND), tuberculosis, and atherosclerosis. The rs1024611 (alleles:A>G; G is the risk allele) polymorphism in the CCL2 ci...

Descripción completa

Detalles Bibliográficos
Autores principales:	Akhtar, Feroz, Ruiz, Joselin Hernandez, Liu, Ya-Guang, Resendez, Roy G., Feliers, Denis, Morales, Liza D., Diaz-Badillo, Alvaro, Lehman, Donna M., Arya, Rector, Lopez-Alvarenga, Juan Carlos, Blangero, John, Duggirala, Ravindranath, Mummidi, Srinivas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635030/ https://www.ncbi.nlm.nih.gov/pubmed/37961304 http://dx.doi.org/10.1101/2023.10.31.564937

Ejemplares similares

The rs1024611 Regulatory Region Polymorphism Is Associated with CCL2 Allelic Expression Imbalance
por: Pham, Minh-Hieu T., et al.
Publicado: (2012)

Impact of the rs1024611 Polymorphism of CCL2 on the Pathophysiology and Outcome of Primary Myelofibrosis
por: Masselli, Elena, et al.
Publicado: (2021)

CCL2 rs1024611Gene Polymorphism in Philadelphia-Negative Myeloproliferative Neoplasms
por: Hodeib, Hossam, et al.
Publicado: (2022)

The rs1024611 in the CCL2 gene and risk of gynecological cancer in Asians: a meta-analysis
por: He, Shuying, et al.
Publicado: (2018)

Genetic Association of the C-C Motif Chemokine Ligand 2 (CCL2) rs1024611 Polymorphism With Periodontitis
por: Ahmed Khan, Hooriyah Laiq, et al.
Publicado: (2023)

Serum carotenoids and Pediatric Metabolic Index predict insulin sensitivity in Mexican American children
por: Mummidi, Srinivas, et al.
Publicado: (2021)

CCL2 single nucleotide polymorphism of rs1024611 implicates prominence of inflammatory cascade by univariate modeling in Indian AMD
por: Sharma, Neel Kamal, et al.
Publicado: (2018)

Association of MCP-1 rs1024611 polymorphism with diabetic foot ulcers
por: Su, Na, et al.
Publicado: (2018)

Association of HIV-1 Infection and Antiretroviral Therapy With Type 2 Diabetes in the Hispanic Population of the Rio Grande Valley, Texas, USA
por: Lopez-Alvarenga, Juan Carlos, et al.
Publicado: (2021)

The MCP‐1 rs1024611 and MTHFR rs1801133 gene variations and expressions in alopecia areata: A pilot study
por: Tabatabaei‐Panah, Pardis‐Sadat, et al.
Publicado: (2021)

Acanthosis nigricans as a composite marker of cardiometabolic risk and its complex association with obesity and insulin resistance in Mexican American children
por: Lopez-Alvarenga, Juan C., et al.
Publicado: (2020)

Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
por: Yi, Jie, et al.
Publicado: (2010)

Study on the association between the polymorphism of MCP-1 rs1024611 and the genetic susceptibility of type 2 diabetes with sepsis
por: Li, Yan, et al.
Publicado: (2022)

Evidence for bivariate linkage of obesity and HDL-C levels in the Framingham Heart Study
por: Arya, Rector, et al.
Publicado: (2003)

MCD Diet Modulates HuR and Oxidative Stress-Related HuR Targets in Rats
por: Ferrigno, Andrea, et al.
Publicado: (2023)

Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2019)

Interplay between RNA-binding protein HuR and Nox4 as a novel therapeutic target in diabetic kidney disease
por: Shi, Qian, et al.
Publicado: (2020)

Tyrosine phosphorylation of HuR by JAK3 triggers dissociation and degradation of HuR target mRNAs
por: Yoon, Je-Hyun, et al.
Publicado: (2014)

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
por: Kaur, Kawaljit, et al.
Publicado: (2017)

Correction: Circ-HuR suppresses HuR expression and gastric cancer progression by inhibiting CNBP transactivation
por: Yang, Feng, et al.
Publicado: (2023)

Association of CCL5 rs2107538, and CCL2 rs3760396 Gene Polymorphisms with the Risk of Cardiovascular Disease
por: Mohtavinejad, Naser, et al.
Publicado: (2021)

Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype
por: Jenkinson, Christopher P., et al.
Publicado: (2015)

HuB and HuD repress telomerase activity by dissociating HuR from TERC
por: Cheng, Xiaolei, et al.
Publicado: (2021)

Association between the MCP-1 -2518 A > G (rs1024611) polymorphism and susceptibility to type 2 diabetes mellitus and diabetic nephropathy: a meta-analysis
por: Chang, Wei-wei, et al.
Publicado: (2023)

Regulation of HuR by DNA Damage Response Kinases
por: Kim, Hyeon Ho, et al.
Publicado: (2010)

Regulation of HuR structure and function by dihydrotanshinone-I
por: Lal, Preet, et al.
Publicado: (2017)

Hu Antigen R (HuR) Protein Structure, Function and Regulation in Hepatobiliary Tumors
por: Lachiondo-Ortega, Sofia, et al.
Publicado: (2022)

Regulation of AT1R expression through HuR by insulin
por: Paukku, Kirsi, et al.
Publicado: (2012)

MiR-200c and HuR in ovarian cancer
por: Prislei, Silvia, et al.
Publicado: (2013)

HuR regulates telomerase activity through TERC methylation
por: Tang, Hao, et al.
Publicado: (2018)

Glycyrrhetinic Acid Maintains Intestinal Homeostasis via HuR
por: Chen, Gang, et al.
Publicado: (2019)

The RNA-Binding Protein HuR in Digestive System Tumors
por: Song, Xiaoqing, et al.
Publicado: (2020)

HuR modulation counteracts lipopolysaccharide response in murine macrophages
por: Bonomo, Isabelle, et al.
Publicado: (2023)

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth
por: Liebig, Janika K., et al.
Publicado: (2020)

Data on genetic associations of carotid atherosclerosis markers in Mexican American and European American rheumatoid arthritis subjects
por: Arya, Rector, et al.
Publicado: (2018)

Different modes of interaction by TIAR and HuR with target RNA and DNA
por: Kim, Henry S., et al.
Publicado: (2011)

The Role of HuR in the Post-Transcriptional Regulation of Interleukin-3 in T Cells
por: González-Feliciano, José A., et al.
Publicado: (2014)

Clinical Significance and Biological Role of HuR in Head and Neck Carcinomas
por: Levidou, Georgia, et al.
Publicado: (2018)

The RNA-binding protein HuR is a negative regulator in adipogenesis
por: Siang, Diana Teh Chee, et al.
Publicado: (2020)

HuR Protein in Hepatocellular Carcinoma: Implications in Development, Prognosis and Treatment
por: Papatheofani, Vasiliki, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t6sdune1cbpa8bc9grtkbfu0de