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Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety

Liraglutide and other agonists of the glucagon-like peptide 1 receptor (GLP-1RAs) are effective weight loss drugs, but how they suppress appetite remains unclear. GLP-1RAs inhibit hunger-promoting Agouti-related peptide (AgRP) neurons of the arcuate hypothalamus (Arc) but only indirectly, implicatin...

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Detalles Bibliográficos
Autores principales: Webster, Addison N., Becker, Jordan J., Li, Chia, Schwalbe, Dana C., Kerspern, Damien, Karolczak, Eva O., Godschall, Elizabeth N., Belmont-Rausch, Dylan Matthew, Pers, Tune H., Lutas, Andrew, Habib, Naomi, Güler, Ali D., Krashes, Michael J., Campbell, John N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635031/
https://www.ncbi.nlm.nih.gov/pubmed/37961449
http://dx.doi.org/10.1101/2023.10.31.564990