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A single locus determines praziquantel response in Schistosoma mansoni

We previously performed a genome-wide association study (GWAS) to identify the genetic basis of praziquantel (PZQ) response in schistosomes, identifying two quantitative trait loci (QTL) situated on chromosome 2 and chromosome 3. We reanalyzed this GWAS using the latest (v10) genome assembly showing...

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Detalles Bibliográficos
Autores principales: Chevalier, Frédéric D., Clec’h, Winka Le, Berriman, Matthew, Anderson, Timothy J.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635054/
https://www.ncbi.nlm.nih.gov/pubmed/37961217
http://dx.doi.org/10.1101/2023.11.01.565202