Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity

Extracellular vesicles (EVs) are generated by all cells and systemic administration of allogenic EVs derived from epithelial and mesenchymal cells have been shown to be safe, despite carrying an array of functional molecules, including thousands of proteins. To address whether epithelial cells deriv...

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Detalles Bibliográficos
Autores principales: Kugeratski, Fernanda G., LeBleu, Valerie S., Dowlatshahi, Dara P., Sugimoto, Hikaru, Arian, Kent A., Fan, Yibo, Huang, Li, Wells, Danielle, Lilla, Sergio, Hodge, Kelly, Zanivan, Sara, McAndrews, Kathleen M., Kalluri, Raghu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635085/
https://www.ncbi.nlm.nih.gov/pubmed/37961535
http://dx.doi.org/10.1101/2023.11.02.565371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635085/
https://www.ncbi.nlm.nih.gov/pubmed/37961535
http://dx.doi.org/10.1101/2023.11.02.565371

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