Design rules for efficient endosomal escape

The inefficient translocation of proteins across biological membranes limits their application as therapeutic compounds and research tools. In most cases, translocation involves two steps: uptake into the endocytic pathway and endosomal escape. Certain charged or amphiphilic molecules promote protei...

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Detalles Bibliográficos
Autores principales: Zoltek, Madeline, Vázquez, Angel, Zhang, Xizi, Dadina, Neville, Lesiak, Lauren, Schepartz, Alanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635116/
https://www.ncbi.nlm.nih.gov/pubmed/37961597
http://dx.doi.org/10.1101/2023.11.03.565388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635116/
https://www.ncbi.nlm.nih.gov/pubmed/37961597
http://dx.doi.org/10.1101/2023.11.03.565388

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