Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4(+) T cells

HIV can persist in a latent form as integrated DNA (provirus) in resting CD4(+) T cells of infected individuals and as such is unaffected by antiretroviral therapy (ART). Despite being a major obstacle for eradication efforts, the genetic variation and timing of formation of this latent reservoir re...

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Detalles Bibliográficos
Autores principales: Sambaturu, Narmada, Fray, Emily J., Wu, Fengting, Zitzmann, Carolin, Simonetti, Francesco R., Barouch, Dan H., Siliciano, Janet D., Siliciano, Robert F., Ribeiro, Ruy M., Perelson, Alan S., Molina-París, Carmen, Leitner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635124/
https://www.ncbi.nlm.nih.gov/pubmed/37961482
http://dx.doi.org/10.1101/2023.11.03.565539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635124/
https://www.ncbi.nlm.nih.gov/pubmed/37961482
http://dx.doi.org/10.1101/2023.11.03.565539

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