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Last in first out: SIV proviruses seeded later in infection are harbored in short-lived CD4(+) T cells
HIV can persist in a latent form as integrated DNA (provirus) in resting CD4(+) T cells of infected individuals and as such is unaffected by antiretroviral therapy (ART). Despite being a major obstacle for eradication efforts, the genetic variation and timing of formation of this latent reservoir re...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635124/ https://www.ncbi.nlm.nih.gov/pubmed/37961482 http://dx.doi.org/10.1101/2023.11.03.565539 |