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A novel stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids

Tailed bacteriophages are one of the most numerous and diverse group of viruses. They store their genome at quasi-crystalline densities in capsids built from multiple copies of proteins adopting the HK97-fold. The high density of the genome exerts an internal pressure, requiring a maturation process...

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Detalles Bibliográficos
Autores principales: Podgorski, Jennifer M., Podgorski, Joshua, Abad, Lawrence, Jacobs-Sera, Deborah, Freeman, Krista G., Brown, Colin, Hatfull, Graham, Luque, Antoni, White, Simon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635136/
https://www.ncbi.nlm.nih.gov/pubmed/37961133
http://dx.doi.org/10.1101/2023.11.03.565530