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Micrococcal nuclease regulates biofilm formation and dispersal in methicillin-resistant Staphylococcus aureus USA300

Biofilm formation is an important virulence factor for methicillin-resistant Staphylococcus aureus (MRSA). The extracellular matrix of MRSA biofilms contains significant amounts of double-stranded DNA. MRSA cells also secrete micrococcal nuclease (Nuc1) which degrades double-stranded DNA. In this st...

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Detalles Bibliográficos
Autores principales: Kaplan, Jeffrey B., Florjanczyk, Aleksandr P., Ochiai, Maria, Jones, Caleb D., Horswill, Alexander R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635163/
https://www.ncbi.nlm.nih.gov/pubmed/37961602
http://dx.doi.org/10.1101/2023.11.05.565664