Clostridioides difficile MreE (PBP2) variants facilitate clinical disease during cephalosporin exposures

Cephalosporins are the most common triggers of healthcare-associated Clostridioides difficile infections (CDI). Here, we confirm gene-level drivers of cephalosporin resistance and their roles in promoting disease. Genomic-epidemiologic analyses of 306 C. difficile isolates from a hospital surveillan...

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Detalles Bibliográficos
Autores principales: Worley, Jay Noboru, Benedetto, Nicholas D., Delaney, Mary, Paiva, Ana Oliveira, Chapot-Chartier, Marie-Pierre, Peltier, Johann, Bry, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635175/
https://www.ncbi.nlm.nih.gov/pubmed/37961251
http://dx.doi.org/10.1101/2023.10.23.23297415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635175/
https://www.ncbi.nlm.nih.gov/pubmed/37961251
http://dx.doi.org/10.1101/2023.10.23.23297415

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