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Clostridioides difficile MreE (PBP2) variants facilitate clinical disease during cephalosporin exposures
Cephalosporins are the most common triggers of healthcare-associated Clostridioides difficile infections (CDI). Here, we confirm gene-level drivers of cephalosporin resistance and their roles in promoting disease. Genomic-epidemiologic analyses of 306 C. difficile isolates from a hospital surveillan...
Autores principales: | Worley, Jay Noboru, Benedetto, Nicholas D., Delaney, Mary, Paiva, Ana Oliveira, Chapot-Chartier, Marie-Pierre, Peltier, Johann, Bry, Lynn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635175/ https://www.ncbi.nlm.nih.gov/pubmed/37961251 http://dx.doi.org/10.1101/2023.10.23.23297415 |
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