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Adverse Childhood Events, Mood and Anxiety Disorders, and Substance Dependence: Gene X Environment Effects and Moderated Mediation

BACKGROUND: Adverse childhood events (ACEs) contribute to the development of mood and anxiety disorders and substance dependence. However, the extent to which these effects are direct or indirect and whether genetic risk moderates them is unclear. METHODS: We examined associations among ACEs, mood/a...

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Detalles Bibliográficos
Autores principales: Kranzler, Henry R., Davis, Christal N., Feinn, Richard, Jinwala, Zeal, Khan, Yousef, Oikonomou, Ariadni, Silva-Lopez, Damaris, Burton, Isabel, Dixon, Morgan, Milone, Jackson, Ramirez, Sarah, Shifman, Naomi, Levey, Daniel, Gelernter, Joel, Hartwell, Emily E., Kember, Rachel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635185/
https://www.ncbi.nlm.nih.gov/pubmed/37961309
http://dx.doi.org/10.1101/2023.10.24.23297419