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A parametric bootstrap approach for computing confidence intervals for genetic correlations with application to genetically-determined protein-protein networks

Genetic correlation refers to the correlation between genetic determinants of a pair of traits. When using individual-level data, it is typically estimated based on a bivariate model specification where the correlation between the two variables is identifiable and can be estimated from a covariance...

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Detalles Bibliográficos
Autores principales: Tsai, Yi-Ting, Hrytsenko, Yana, Elgart, Michael, Tahir, Usman, Chen, Zsu-Zsu, Wilson, James G, Gerszten, Robert, Sofer, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635196/
https://www.ncbi.nlm.nih.gov/pubmed/37961678
http://dx.doi.org/10.1101/2023.10.24.23297474