CYP2C19 Polymorphisms and Clinical Outcomes Following Percutaneous Coronary Intervention (PCI) in the Million Veterans Program

BACKGROUND: CYP2C19 loss-of-function (LOF) alleles decrease the antiplatelet effect of clopidogrel following percutaneous coronary intervention (PCI) in patients presenting with acute coronary syndrome (ACS). The impact of genotype in stable ischemic heart disease (SIHD) is unclear. OBJECTIVES: Dete...

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Detalles Bibliográficos
Autores principales: Chanfreau-Coffinier, Catherine, Friede, Kevin A., Plomondon, Mary E., Lee, Kyung Min, Lu, Zhenyu, Lynch, Julie A., DuVall, Scott L., Vassy, Jason L., Waldo, Stephen W., Cleator, John H., Maddox, Thomas M., Rader, Daniel J., Assimes, Themistocles L., Damrauer, Scott M., Tsao, Philip S., Chang, Kyong-Mi, Voora, Deepak, Giri, Jay, Tuteja, Sony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635203/
https://www.ncbi.nlm.nih.gov/pubmed/37961335
http://dx.doi.org/10.1101/2023.10.25.23297578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10635203/
https://www.ncbi.nlm.nih.gov/pubmed/37961335
http://dx.doi.org/10.1101/2023.10.25.23297578

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